Peptide comparison
Wolverine vs GLOW vs KLOW
These three blends build on each other. Wolverine combines BPC-157 and TB-500. GLOW adds the copper peptide GHK-Cu. KLOW adds the tripeptide KPV on top of that. None of the blends has been studied as a mixture, so everything known about them comes from their individual components.
Reviewed by the Helica Labs research team · Last updated October 10, 2026
| Wolverine | GLOW | KLOW | |
|---|---|---|---|
| What it is | Wolverine Two-peptide blend: BPC-157 and TB-500. | GLOW Three-peptide blend: BPC-157, TB-500 and GHK-Cu. | KLOW Four-peptide blend: everything in GLOW plus KPV. |
| Sequence and composition | Wolverine Per vial: BPC-157 and TB-500 in equal amounts, 5 mg + 5 mg or 10 mg + 10 mg. | GLOW Per vial: GHK-Cu 50 mg, BPC-157 10 mg, TB-500 10 mg. 70 mg of peptide in total, about 71% of it GHK-Cu. | KLOW Per vial: GHK-Cu 50 mg, BPC-157 10 mg, TB-500 10 mg, KPV 10 mg. 80 mg of peptide in total, 62.5% of it GHK-Cu. |
| Proposed mechanism | Wolverine BPC-157 promotes blood-vessel growth and cell migration in animal models. TB-500 binds actin, the protein that shapes the cell skeleton and lets cells migrate. | GLOW The Wolverine pair plus GHK-Cu, which carries copper into cells and influences genes involved in collagen production and remodelling of the extracellular matrix. | KLOW The GLOW components plus KPV, which dampens inflammatory signalling (NF-κB) in cell and animal studies. |
| Half-life | Wolverine Not studied as a blend. BPC-157 is cleared within minutes in rat and dog studies. For TB-500, the only human data are for full-length thymosin beta-4: about 0.5–2 hours after intravenous administration. | GLOW Not studied as a blend. As for Wolverine; GHK-Cu has no established plasma half-life. | KLOW Not studied as a blend. As for GLOW; KPV has no established half-life. |
| Evidence in humans | Wolverine No trials of the combination. BPC-157 human data are limited to a few small reports, about 80 people in total. For the TB-500 fragment there are no human data; human trials used full-length thymosin beta-4. | GLOW No studies of the blend. Components: as for Wolverine; human data on GHK-Cu come mostly from topical cosmetic studies. | KLOW No studies of the blend. Components: as for GLOW; there are no human exposure data for KPV. |
| Regulatory status | Wolverine Neither component is an approved medicine. BPC-157 is prohibited in sport under WADA S0 and TB-500 under S2. | GLOW None of the components is an approved medicine. Contains BPC-157 (WADA S0) and TB-500 (WADA S2). | KLOW None of the components is an approved medicine. Contains BPC-157 (WADA S0) and TB-500 (WADA S2). |
The components
- BPC-157
- A synthetic 15-amino-acid peptide (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) derived from a sequence in a protein found in human gastric juice. Studied mainly in animal models of tissue repair.
- TB-500
- A synthetic peptide based on the actin-binding region of thymosin beta-4. Usually the short fragment Ac-LKKTETQ, though some products contain full-length thymosin beta-4; the certificate of analysis should state which.
- GHK-Cu
- The copper(II) complex of the tripeptide Gly-His-Lys, which occurs naturally in human plasma. Known in skincare as copper tripeptide-1.
- KPV
- The tripeptide Lys-Pro-Val, the C-terminal end (residues 11–13) of alpha-melanocyte-stimulating hormone (α-MSH). Studied for anti-inflammatory effects in cell and animal models.
Key differences
- Each blend contains the one before it: Wolverine is BPC-157 + TB-500, GLOW adds GHK-Cu, and KLOW adds KPV.
- GHK-Cu makes up most of GLOW and KLOW by mass, so both contain copper. Wolverine does not.
- The ratio of components is fixed in each vial and cannot be changed after reconstitution.
- All three contain BPC-157 and TB-500, which are on the WADA Prohibited List.
- None of the blends has been studied as a mixture, so interactions between the components are unknown.
For research use only. Not for human consumption. Always verify against current literature.
Frequently asked questions
- What is the difference between GLOW, KLOW and Wolverine?
- Wolverine contains BPC-157 and TB-500. GLOW contains those two plus GHK-Cu. KLOW contains everything in GLOW plus KPV. By mass, GLOW and KLOW are mostly GHK-Cu, while Wolverine is an even split of its two peptides.
- What is in a KLOW vial?
- GHK-Cu 50 mg, BPC-157 10 mg, TB-500 10 mg and KPV 10 mg: 80 mg of peptide in total.
- Have GLOW, KLOW or Wolverine been studied?
- Not as blends. There are no published studies of GLOW, KLOW or Wolverine as mixtures. Evidence exists only for the individual components, and most of it comes from animal or cell studies.
- What is the half-life of GLOW, KLOW and Wolverine?
- No blend has a measured half-life. Of the components, BPC-157 is cleared within minutes in animal studies, full-length thymosin beta-4 has a half-life of about 0.5–2 hours after intravenous administration in humans, and GHK-Cu and KPV have no established values.
- Are GLOW, KLOW and Wolverine allowed in sport?
- No. All three contain BPC-157, which WADA lists under S0 (non-approved substances), and TB-500, which WADA lists under S2 as a thymosin beta-4 derivative.