Research library

Peptide Encyclopedia

Evidence-based reference guides for research peptides — mechanisms, what the research shows, community-reported use, and citations. For research use only; not medical advice.

Metabolic

Retatrutide

Investigational once-weekly triple agonist (GIP/GLP-1/glucagon) by Eli Lilly; phase 2 data show large weight loss. Not approved.

Metabolic

Tirzepatide

Dual GIP/GLP-1 receptor agonist with strong human trial evidence for type 2 diabetes glycemic control and weight reduction.

Metabolic

Semaglutide

GLP-1 receptor agonist with strong human-trial evidence for weight loss, glycemic control, and cardiovascular risk reduction.

Metabolic

Liraglutide

GLP-1 receptor agonist with strong human-trial evidence for type 2 diabetes glycemic control, weight management, and cardiovascular risk reduction; dosed once daily.

Recovery

BPC-157

A synthetic gastric pentadecapeptide studied for tissue repair. Evidence is largely preclinical; human data is minimal. Research use only.

Recovery

TB-500

Synthetic actin-binding peptide studied for tissue repair; strong preclinical data but limited human evidence for musculoskeletal use.

Metabolic

Survodutide

Investigational once-weekly glucagon/GLP-1 receptor dual agonist (BI 456906) from Boehringer Ingelheim/Zealand Pharma; phase 2 obesity and MASH data. Not approved.

Hormonal

CJC-1295

A synthetic GHRH analog studied for stimulating growth hormone and IGF-1 release; not approved for human use.

Hormonal

CJC-1295 + Ipamorelin

A research blend pairing a GHRH analog (CJC-1295) with a selective ghrelin-receptor agonist (Ipamorelin) to stimulate pulsatile growth hormone release.

Longevity

Epitalon

Synthetic pineal tetrapeptide (Ala-Glu-Asp-Gly) studied as a telomerase activator; human evidence is limited and mostly from one Russian group.

Aesthetic

GHK-Cu

Copper-binding tripeptide studied mainly topically for collagen synthesis, skin repair and wound healing; human evidence is largely cosmetic.

Blend

GLOW

Research-only blend of GHK-Cu, BPC-157 and TB-500 marketed for skin and tissue repair; component data is mostly preclinical.

Hormonal

Ipamorelin

A selective ghrelin-receptor agonist that stimulates pulsatile GH release; human data limited and it is not an approved drug.

Metabolic

MOTS-c

Mitochondrial-derived peptide studied preclinically for AMPK activation, insulin sensitivity and exercise capacity; no approved human therapy.

Longevity

NAD+

NAD+ is a core metabolic coenzyme; boosting it is widely studied for aging, but human benefit data remain limited and mixed.

Blend

Wolverine (BPC-157 + TB-500)

Research blend of BPC-157 and TB-500 explored for tissue repair. Evidence is largely preclinical; combination synergy in humans is unproven.

Recovery

KPV

Anti-inflammatory tripeptide from alpha-MSH; promising preclinical gut/skin data, no human efficacy trials. Research use only.

Blend

KLOW

Research-only 4-peptide blend (GHK-Cu, BPC-157, TB-500, KPV) studied for tissue repair and inflammation; human evidence is limited.

Metabolic

5-Amino-1MQ

A small-molecule inhibitor of the enzyme NNMT studied in rodent obesity and muscle models; zero human trial data; research use only.

Metabolic

AOD-9604

A synthetic C-terminal fragment of human growth hormone studied for fat metabolism; failed its pivotal obesity trial but has human safety data and FDA food-ingredient GRAS...

Recovery

ARA-290

An 11-amino-acid synthetic peptide derived from erythropoietin (EPO), engineered to activate the innate repair receptor without stimulating red blood cell production; studied...

Metabolic

Cagrilintide

A long-acting acylated amylin analogue under clinical development by Novo Nordisk, studied primarily in combination with semaglutide for obesity; research use only.

Cognitive

DSIP

A naturally occurring nonapeptide originally linked to delta-wave sleep, with intriguing but inconsistent and poorly characterized evidence. Research use only.

Longevity

FOXO4-DRI

FOXO4-DRI is a protease-resistant D-retro-inverso peptide designed to selectively induce apoptosis in senescent cells by disrupting the FOXO4–p53 interaction, with efficacy...

Hormonal

GHRP-2

A synthetic growth-hormone secretagogue and ghrelin-receptor agonist that triggers pulsatile GH release; backed by real human pharmacology data and a Japanese diagnostic...

Hormonal

GHRP-6

The prototypical growth-hormone-releasing peptide and ghrelin-receptor agonist, best known for strongly stimulating both GH release and appetite; characterized human...

Longevity

Glutathione

The body's primary intracellular antioxidant tripeptide, synthesized endogenously. Studied via IV, liposomal oral, and other routes for antioxidant support, neurological...

Hormonal

HCG

A glycoprotein gonadotropin that acts as an LH-receptor agonist; FDA-approved for hypogonadism, cryptorchidism, and ovulation induction, though often encountered in research or...

Hormonal

HGH

Recombinant human growth hormone (somatropin), an FDA-approved 191-amino-acid hormone for defined deficiency states; widely diverted off-label for anti-aging and performance...

Hormonal

HMG

A urinary-derived gonadotropin preparation containing approximately equal FSH and LH bioactivity, FDA-approved for ovarian stimulation in ART and male hypogonadotropic...

Hormonal

IGF-1 LR3

A synthetic long-acting IGF-1 analogue widely used as a cell culture reagent; studied in animal models for anabolic, anti-catabolic, and tissue-growth effects. No approved...

Hormonal

Kisspeptin-10

The C-terminal decapeptide of kisspeptin, acting as a potent GPR54/KISS1R agonist that stimulates GnRH pulsatility and downstream sex hormone release; supported by multiple...

Metabolic

L-Carnitine

A naturally occurring amino-acid derivative that carries fatty acids into mitochondria for energy. An approved drug for carnitine deficiency; evidence for fat loss is mixed.

Recovery

LL-37

The only human cathelicidin — a 37-amino-acid host defence peptide cleaved from hCAP-18 — with direct antimicrobial, immunomodulatory, and wound-healing activities studied...

Aesthetic

MT-1

Afamelanotide (MT-1) is a synthetic MC1R-selective alpha-MSH analogue that stimulates eumelanin production, approved as Scenesse for erythropoietic protoporphyria (EPP) and...

Aesthetic

MT-2

A synthetic, non-selective melanocortin receptor agonist studied for skin tanning and erectile dysfunction; never approved by any regulatory authority and associated with...

Cognitive

Oxytocin

A natural nine-amino-acid neuropeptide approved for obstetric use, but whose intranasal use for social and psychiatric outcomes is experimental with mixed evidence. Research...

Hormonal

PEG-MGF

A PEGylated synthetic form of mechano growth factor (the IGF-1Ec splice variant), studied preclinically for muscle satellite cell activation, cardioprotection, and...

Longevity

Pinealon

A synthetic Glu-Asp-Arg tripeptide from Vladimir Khavinson's peptide bioregulator class, with proposed neuroprotective and epigenetic-regulatory mechanisms studied almost...

Aesthetic

PT-141

PT-141 (bremelanotide) is an FDA-approved melanocortin receptor agonist — marketed as Vyleesi — indicated for hypoactive sexual desire disorder (HSDD) in premenopausal...

Cognitive

Selank

A synthetic tuftsin-derived heptapeptide studied as an anxiolytic and mild nootropic, with most efficacy data from Russian clinical practice rather than international trials....

Cognitive

Semax

A synthetic ACTH(4-10)-derived heptapeptide studied as a neuroprotective nootropic, used in Russia for stroke and cognitive indications but unapproved elsewhere. Research use only.

Hormonal

Sermorelin

A synthetic 29-amino-acid fragment of GHRH that prompts the pituitary to release its own growth hormone; formerly FDA-approved for pediatric GH deficiency, now used off-label...

Aesthetic

SNAP-8

Topical cosmetic peptide (acetyl octapeptide-3) for serums/creams - never injected. An Argireline relative for expression lines; evidence is mostly manufacturer data.

Longevity

SS-31

An aromatic-cationic mitochondria-targeted tetrapeptide that selectively concentrates at the inner mitochondrial membrane by binding cardiolipin; it has reached Phase II...

Hormonal

Tesamorelin

A synthetic GHRH analogue that is FDA-approved for HIV-associated lipodystrophy; studied in research settings for visceral fat reduction, hepatic steatosis, and cognitive...

Longevity

Thymalin

Polypeptide bioregulator derived from bovine thymus gland, studied in Russia for immune restoration and longevity; most evidence is from a single research group, with no FDA or...

Longevity

Thymosin Alpha-1

Thymosin Alpha-1 (Tα1) is a 28-amino-acid thymic peptide with well-documented immunomodulatory activity. It is approved in over 35 countries as Zadaxin (thymalfasin) for...

Recovery

VIP

A 28-amino-acid endogenous neuropeptide with pleiotropic vasodilatory and anti-inflammatory effects; aviptadil (synthetic VIP) has been evaluated in Phase 2/3 human trials for...

Aesthetic

Lipo-C

Compounded lipotropic (MIC) injection of methionine, inositol and choline marketed for fat metabolism; weak weight-loss evidence.