TB-500

TB-500 is a synthetic peptide widely marketed as a fragment/analog of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid protein found in platelets, white blood cells, and other tissues that plays a central role in cell migration, actin regulation, and tissue repair. The injectable products sold as "TB-500" typically contain a short active fragment of Tβ4 (often the actin-binding region) rather than the full-length protein, though labeling and purity vary widely in the research-chemical market. Most of the rigorous evidence comes from full-length Tβ4 in animal models and a handful of company-sponsored human trials in specific indications such as corneal/eye injury, dry eye, and cardiac repair. Evidence specifically for the "TB-500" fragment in athletic recovery, tendon, ligament, or muscle injury is largely preclinical or anecdotal. It is sold strictly as a research chemical and is not approved for human therapeutic use in recovery or performance contexts. It is also banned in competitive sport. This profile is provided for research reference only and is not medical advice.